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This activation: Promotes directed cell migration toward injury sites Enhances cellular outgrowth from damaged tissue edges Improves cell survival during the stressful healing process Facilitates proper tissue organization This mechanism is particularly relevant for tendon and ligament healing, where cellular organization and proper fiber alignment are critical for functional recovery
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Ultimately, the NF-κB-Nrf2 pathway amplifies PQQ anti-inflammatory and antioxidative effects, thereby protecting animals with a PE-like model (Wang et al., 2022b)
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